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Monday

We provide routine 24x7 clinical biochemistry and hormone analysis services to the patients.

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Tuesday

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Wednesday

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Thursday

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Friday

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Saturday

Visiting Scientist

Children’s Hospital Oakland Research Institute, Oakland, California, USA

 July 2017

Senior Postdoctoral Fellow                        

Jan 2011-Aug 2012

Postdoctoral Fellow

Children’s Hospital Oakland Research Institute, Oakland, California, USA        

Sept 2007-Dec2010

Texas A&M Health Science Centre, Temple, Texas, USA

Dec 2006-Aug 2007

Central Military Veterinary Laboratory, Meerut, India

Aug2000-Mar 2001

CSIR-UGC Junior/Senior Research Fellowship

Jan 2002-Dec 2006

Nema R, Saluja R and Kumar A (2024) Editorial: Regulation of tumor-immune microenvironment by non-coding RNAs. Front. Immunol. 15:1362881.

10.3389/fimmu.2024.1362881

PubMed

Tiwari A, Kumari B, Nandagopal S, Mishra A, Shukla KK, Kumar A, Dutt N, Ahirwar DK. Promises of Protein Kinase Inhibitors in Recalcitrant Small-Cell Lung Cancer: Recent Scenario and Future Possibilities. Cancers. 2024; 16(5):963.

Fulltext

Nema R, Pandey R, Kumar A. ROR1/2 and S1P Signaling Pathways Crosstalk in Lung Cancer Cells. Asian Pacific Journal of Cancer Prevention. 2024 Mar 1;25(3):725-733.

PubMed

Tomar MS, Kumar A,Shrivastava A. Mitochondrial metabolism as a dynamic regulatory hub to malignant transformation and anti-cancer drug resistance. Biochemical and Biophysical Research Communications. 2023;624:  149382

PubMed

Jose A, Kulkarni P, Thilakan J, Munisamy M, Malhotra AG, Singh J, Kumar A, Rangnekar VM, Rao M, Arya N. Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine. Molecular Cancer (Accepted).

PubMed

Sindhuja, Kumar A, Bhatia G, Gupta S, Kumar A. Primary hypoparathyroidism associated with catatonia in a patient with Bipolar affective disorder: A case report. Psychiatry Research Case Reports. 2024;3: 100196

Full Text

Sadique MA, Yadav S, Ranjan P, Chouhan RS, Jerman I, Kumar A, Saigal S, Khadanga S,  Khan R, Shrivastava, A. Detection of specific antibodies against SARS-CoV-2 spike protein via ultra-sensitive bio-functionalized carbon-nitride reduced graphene oxide electrochemical immunosensing platform in real samples. Material Advances.2023;4:5291.

10.1039/D3MA00399J

Full Text

Singh H, Khurana A, Kumar A and Saluja R. Serum Levels of Interleukin-33, soluble ST2 and IgE in patients with Asthma: A case-control study. Journal of Asthma. 2023. 1-8

doi: 10.1080/02770903.2023.2244579; PMID: 37548422

PubMed

Tiwari S, Pandey R, Kumar V, Das S, Gupta V, Vishwakarma S, Nema R, Sindhuja T, Hashmi S, Kumar A. Association of single nucleotide polymorphism miRNA-146a (rs2910164) with increased predisposition to oral squamous cell carcinoma in central India population. Cancer Biomark. 2023;38(2):203-214.

doi: 10.3233/CBM-230064. PMID: 37545224.

PubMed

Poorvaragavan P, Vidua RK, Kumar A, Ponmani P, Ketche S A, Sahoo Niranjan. Estimation of Time Since Death Using Biochemical Markers in Synovial fluid. American Journal of Forensic medicine and Pathology. 2023. Jul 21.

doi: 10.1097/PAF.0000000000000861; PMID: 37486956

PubMed

17. Pandey R, Nema R, Vishwakarma S, Singh AP, Mohan S, Patel P, Halder S, Halder A, Singh R, Agarwal R, Gupta V, Kumar A. Association of single nucleotide polymorphisms in cytokine genes with the susceptibility of oral squamous cell carcinomas (OSCC) in central Indian patients (Asian Pacific Journal of Cancer Prevention. 2023 Jul 1;24(7):2353-2360.

doi: 10.31557/APJCP.2023.24.7.2353.

PubMed

Kumari A, Jha A, Tiwari A, Nath N, Kumar A, Nagini S, Mishra R. Role and regulation of GLUT1/ 3 during oral cancer progression and therapy resistance. Archives of Oral Biology. 2023; 150:105688. (PMID: 36989865)

https://doi.org/10.1016/j

PubMed

Joshi B, Kaur J, Khan E, Vishwakarma S, Kumar A, Joshi D, Kumar A*, Joshi A. Alginate-based ‘nano-micro’ hybrid matrices developed using ultrasonic atomization for co-delivery of chemotherapeutic drugs against superficial tumors. Journal of Drug Delivery Science and Technology. 2023; 84: 104532 Impact Factor 5.0.* Corresponding author.

https://doi.org/10.1016/j

Science Direct

Joshi B, Shankar U, Vishwakarma S, Kumar A, Kumar A, Joshi D, Joshi A. Multifunctional Ultrasmall Theranostic Nanohybrids Developed by Ultrasonic Atomizer for Drug Delivery and Magnetic Resonance Imaging. ACS Appl Bio Mater. 2023 May 15;6(5):1943-1952.

doi.org/10.1021/acsabm.3c00151

PubMed

Joshi S, Pandey R, Kumar A, Gupta V, and Arya N. Targeted blockade of interleukin-8 negates metastasis and chemoresistance via Akt/Erk-NFκB axis in oral cancer. Cytokine 2023 Apr 21;166:156155.

doi: 10.1016/j.cyto.2023.156155.

PubMed

Kumari R, Tiwari S, Atlani M, Anirudhan A, Goel SK, Kumar A. Association of Single nucleotide polymorphisms in KCNA10 and SLC13A3 genes with the susceptibility to Chronic Kidney Disease of unknown etiology in central Indian patients. Biochemical Genetics. 2023 Jan 25. Epub ahead of print. PMID: 36696070

doi: 10.1007/s10528-023-10335-7.

PubMed

Chatterjee A, Rakshit S, Sanmugam G, Mohanty LM, Kumar A, Harihar S, Sarkar K. Neem Leaf Glycoprotein mediated epigenetic modification in Oral Squamous Cell Carcinoma. Phytomedicine Plus. 2023; 3(1)100400.

doi.org/10.1016/j.phyplu.2022.100400

Full Text

Khurana S, Singh AP, Kumar A, Nema R. Prognostic value of AKT isoforms in non-small cell lung adenocarcinoma[J]. The Journal of Biomedical Research. 2022 Nov 10:1-4.

doi: 10.7555/JBR.36.20220138

PubMed

Shivhare A, Jain A, Sharma JP, Kaushal A, Kumar H, Kumar A. Intravascular volume status and stress markers in patients observing long and short duration of fasting: A prospective single blinded observational study. Journal of Clinical Anesthesia.

doi: 10.1016/j.jclinane.2022.110992.

PubMed

Jain S, Singh AP, Kumar A, Saluja R and Nema R. Stem cells Research prospects towards precision medicine. Bratislava Medical Journal (Bratisl Lek Listy) 2022;123(11):795-805

doi:10.4149/BLL_2022_128

PubMed

Atlani M, Kumar A, Pakhare A P, Potential Association of Hypernatremia With Mortality in Patients With Acute Kidney Injury and COVID-19. Cureus. 2022 14(7): e27530.

doi:10.7759/cureus.27530

PubMed

de la garza-Rodea A, Moore SA, Zamora-Pineda J, Hoffman EH, Mistry K, Kumar A, Strober JB, Zhao P, Suh JH, Saba JD. Sphingosine Phosphate Lyase Is Upregulated in Duchenne Muscular Dystrophy, and Its Inhibition Early in Life Attenuates Inflammation and Dystrophy in Mdx Mice. International Journal of Molecular Sciences. 2022; 23(14): 7579 (IF 5.5)

https://doi.org/10.3390/ijms23147579

PubMed

Sadique MA, Yadav S, Ranjan P, Khan R, Khan F, Kumar A, Biswas D. Highly Sensitive Electrochemical Immunosensor Platforms for Dual Detection of SARS-CoV-2 Antigen and Antibody based on Gold Nanoparticle Functionalized Graphene Oxide Nanocomposites. ACS Appl Bio Mater. 2022 May 16;5(5):2421-2430. Epub 2022 May 6. PMID: 35522141; PMCID: PMC9113004.

doi: 10.1021/acsabm.2c00301.

PubMed

Tiwari S, Goel G, Kumar A. Natural and genetically-modified animal models to investigate pulmonary and extrapulmonary manifestations of COVID-19. International Reviews of Immunology. 2022 (June). 2089666;

doi.10.1080/08830185.2022.2089666

PubMed

Vishwakarma S, Joshi D, Singh R, Singhal R, Kapoor N, Goel SK, Kumar A. Downregulation of Lipid Phosphate Phosphatase 3 correlates with Tumor-Infiltrating Immune Cells in Oral Cancer. Cureus 2022 Mar 27;14(3):e23553

DOI: 10.21203/rs.3.rs-1043910/v1

PubMed

Vishwakarma S, Arya N and Kumar A. Regulation of tumor immune microenvironment by sphingolipids and lysophosphatidic acid. Current Drug Targets. 2022;23(6):559-573.PMID: 34879798.

doi: 10.2174/1389450122666211208111833.

PubMed

Sadique MA, Yadav S, Ranjan P, Khan R. Rapid Detection of SARS-CoV-2 using Graphene-based IoT Integrated Advanced Electrochemical Biosensor. 2021; 305: 130824. (IF 3.4) (Highlighted by Nature India

https://www.nature.com/articles/d44151-022-00049-x

PubMed

Tomar MS, Kumar A, Srivastava C, Shrivastava A. Elucidating the mechanism of Temozolomide Resistance in gliomas and the strategies to overcome the resistance. Biochim Biophys Acta Rev Cancer. 2021 Aug 20;1876(2):188616.

https://doi.org/10.1016/j.bbcan.2021.188616

PubMed

Chandel V, Maru S, Kumar A, Kumar A, Sharma A, Rathi B, Kumar D. Role of Monocarboxylate Transporters in Head and Neck Squamous Cell Carcinoma. Life Sciences. 2021;279:

https://doi.org/10.1016/j.lfs.2021.119709 (IF 6.7)

PubMed

Nema R, Patel P, Kumar A. Prognostic role of receptor tyrosine kinase–like orphan receptors in intestinal-type gastric cancer. Asian Pacific Journal of Cancer Prevention 2021 Jul 1;22(7):2125-2134 (IF 1.6)

https://doi.org/10.315572FAPJCP.2021.22.7.2125

PubMed

Nema R, and Kumar A. Sphingosine-1-Phosphate Catabolizing Enzymes Predict Better Prognosis in Triple-Negative Breast Cancer Patients and Correlates With Tumor-Infiltrating Immune Cells. (IF 5.2)

https://doi.org/10.3389/fmolb.2021.697922

PubMed

Chaudhary P, Goyal A, Goel SK, Kumar A, Chaudhary S, Kirti Keshri S, Phadke Subhedar R. Women with OSA have higher chances of having metabolic syndrome than men: effect of gender on syndrome Z in cross sectional study. Sleep Med. 2021 Jan 2;79:83-87. (IF 3.6)

https://doi.org/10.1016/j.sleep.2020.12.042

PubMed

Nema R, Shrivastava A and Kumar A. Prognostic role of lipid phosphate phosphatases in non-smoker, lung adenocarcinoma patients. Computers in Biology and Medicine 2021;129: 104141 (IF 4.5)

doi.org/10.1016/j.compbiomed.2020.104141

PubMed

Vishwakarma S, Pandey R, Singh R, Gothalwal R, Kumar A. Expression of H19 long noncoding RNA is down-regulated in Oral Squamous Cell Carcinoma. 2020; 45:145 (IF 2.7)

DOI: 10.1007/s12038-020-00118-2

PubMed

Kumar A, Zamora-Pineda J, Degagné E and Saba JD. S1P lyase regulation of thymic egress and oncogenic inflammatory signaling. Mediators of Inflammation. 2017;2017:7685142. (IF 4.7)

https://doi.org/10.1155/2017/7685142

PubMed

Saluja R, Kumar A, Jain M, Goel SK, Jain M, Goel SK, Jain A. Potential Role of Sphingosine-1-Phosphate in Mast Cell Functions and Asthma and its Regulation by Non-Coding RNA.Frontiers in Immunology 2017 May 22;8:587

https://doi.org/10.3389/fimmu.2017.00587

PubMed

Vishwakarma S, Agarwal R, Goel SK, Panday RK, Singh R, Sukumaran R, Khare S, Kumar A. Altered expression of Sphingosine-1-Phosphate metabolizing enzymes in oral cancer correlate with clinicopathological attributes. Cancer Investigation 2017 Feb 7;35(2):139-141 IF 2.2)

https://doi.org/10.1080/07357907.2016.1272695

PubMed

Kumar A, Zamora-Pineda J, Suh JH, Zhang M, Saba JD. Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress. J Exp. Med. 2016 Oct 17 213(12): 2773-2791

DOI: 10.1084/jem.20160287 IF 14.3)

PubMed

. Nema R, Vishwakarma S, Agarwal R, Panday RK, Kumar A. Emerging Role of Sphingosine-1-Phosphate Signaling in Head and Neck Squamous Cell Carcinoma. OncoTargets and Therapy 2016; May 31;9:3269-80 (Impact Factor 3.8)

https://doi.org/10.2147/OTT.S99989

PubMed

Kumar A and Saba JD. Regulation of Leukocyte trafficking by Sphingosine-1-Phosphate. Cell Mol Biol (OMICS). 2015;61(2):121. PMID: 30294722

doi: 10.4172/1165-158X.1000121.

PubMed

Nema R, Kumar A. Regulation of Mitochondrial Function by Bioactive Sphingolipids. Cell Biology. Special Issue: Mitochondria: Implications in Human Health and Diseases. 2015 Feb; 3(2-1):1-7

doi: 10.11648/j.cb.s.2015030201.11

Full Text

Degagné E, Pandurangan AK, Bandhuvula P, Kumar A, Eltnawy A, Zhang M, Yoshinaga Y, Nefedov M,  de Jong P, Fong LG, Young SG, Bittman R, Ahmedi Y, Saba JD.Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated miRNAs. 2014 Dec;124(12):5368-84.(Impact Factor 14.8)

https://doi.org/10.1172/JCI74188

PubMed

de la Garza-Rodea AS, Baldwin D, Oskouian B, Place Robert, Bandhuvula P, Kumar A, and Saba JD. S1P lyase regulates myogenic differentiation via S1PR-mediated effects on myogenic miRNA expression. FASEB Journal 2014 Jan;28(1):506-19. (Impact Factor 5.0)

https://doi.org/10.1096%2Ffj.13-233155

PubMed

Kumar A, Pandurangan AK, Lu F, Fyrst F, Zhang M, Byun HS, Bittman R, and Saba JD. Chemopreventive Sphingadienes Downregulate Wnt Signaling in Human Colon Cancer Cells and Intestinal Tissues of ApcMin/+ Mice. Carcinogenesis 2012 Sep;33(9):1726-35. (Impact Factor 5.3)

https://doi.org/10.1093/carcin/bgs174

PubMed

Borowsky AD, Bandhuvula P, Kumar A, Yoshinaga Y, Nefedov M, Fong LG, Zhang M, Baridon B, Dillard L, de Jong P, Young SG, West DB, Saba JD. Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues. J Lipid Res. 2012 Sep; 53(9): 1920-31. (Impact Factor 5.9)

https://doi.org/10.1194/jlr.M028084

PubMed

Upadhyaya P, Kumar A, Byun HS, Bittman R, Saba JD, and Hecht SS. The sphingolipid degradation product trans-2-hexadecenal forms adducts with DNA. Biochemical and Biophysical Research Communications 2012 Jul 20;424(1):18-21. (Impact Factor 3.5)

https://doi.org/10.1016/j.bbrc.2012.06.012

PubMed

Loh KC, Leong WI, Carlson ME, Oskouian B, Kumar A, Fyrst F, Zhang M, Proia RL, Hoffman E and Saba JD. Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through an S1PR2/STAT3 signaling pathway. PLoS One 2012, 7(5) e37218 (Impact Factor 3.2)

https://doi.org/10.1371/journal.pone.0037218

PubMed

Smith, G.S.; Kumar, A.; Saba, J.D. Sphingosine Phosphate Lyase Regulates Murine Embryonic Stem Cell Proliferation and Pluripotency through an S1P2/STAT3 Signaling Pathway. Biomolecules 2013, 3, 351-368 (Impact Factor 4.6)

https://doi.org/10.3390/biom3030351

PubMed

Kumar A, Byun HS, Bittman R and Saba JD. The sphingolipid degradation product trans-2-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner. Cellular Signaling 2011 Jul;23(7):1144-52. (Impact Factor 4.0)

https://doi.org/10.1016/j.cellsig.2011.02.009

PubMed

Kumar A, Oskouian B, Fyrst H, Zhang M, Paris F and Saba JD. S1P Lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism. Cell Death & Disease. 2011 2, e119 (Impact Factor 8.4)

10.1038/cddis.2011.3

PubMed

Tandon A, Shrivastava A, Kumar A, Prayaga AK, Sundaram C, Godbole MM. Sodium Iodide Symporter, Estrogen Receptor and Progesterone Receptor Expression in Carcinoma Breast - an Immunohistochemical Analysis. Indian J Pathology and Microbiology. 2011, 54 (4) 745-751. (Impact Factor 0.7) 2009 Aug;13(8):1013-25.

https://doi.org/10.1517/14728220903039722

PubMed

Kumar A and Saba JD. Lyase to live by: Sphingosine phosphate lyase as a therapeutic target. Expert Opin Ther Targets. 2009 Aug;13(8):1013-25. (Impact Factor 6.9)

doi: 10.1517/14728220903039722

PubMed

Sinha RA, Pathak A, Kumar A, Tiwari M, Shrivastava A, Godbole MM. Enhanced neuronal loss under perinatal hypothyroidism involves impaired neurotrophic signaling and increased proteolysis of p75(NTR). Mol Cell Neurosci. 2009 Mar;40(3):354-64 (Impact Factor 3.9).

https://doi.org/10.1016/j.mcn.2008.12.001

PubMed

Tiwari M, Bajpai VK, Sahasrabuddhe AA, Kumar A, Sinha RA, Behari S, Godbole MM. Inhibition of N-(4-hydroxyphenyl) retinamide-induced autophagy at a lower dose enhances apoptosis in malignant glioma cells. Carcinogenesis. 2008 Mar;29(3):600-9. (Impact Factor 5.3).

https://doi.org/10.1093/carcin/bgm264

PubMed

Kumar A, Sinha RA, Tiwari M, Singh R, Koji T, Manhas N, Rastogi L, Pal L, Shrivastava A, Sahu RP, Godbole MM. Hyperthyroidism induces apoptosis in rat liver through activation of death receptor-mediated pathways. Journal of Hepatology 2007; 46(5):888-898.(Impact Factor 25.0)

https://doi.org/10.1016/j.jhep.2006.12.015

PubMed

Tiwari M, Kumar A, Sinha RA, Shrivastava A, Balapure AK, Sharma R, Bajpai VK, Mitra K, Babu S, and Godbole MM. Mechanism of 4-HPR induced apoptosis in glioma cells: Evidences suggesting role of mitochondrial-mediated pathway and endoplasmic reticulum stress. Carcinogenesis 2006; 27(10):2047-2058. (Impact Factor 5.3)

https://doi.org/10.1093/carcin/bgl051

PubMed

Kumar A, Sinha RA, Tiwari M, Pal L, Shrivastava A, Singh R, Kumar K, Gupta SK, and Godbole MM. Increased pro-Nerve Growth Factor and p75NTR levels in developing hypothyroid rat cerebral cortex are associated with enhanced apoptosis. Endocrinology 2006; 147(10):4893-4903. (Impact Factor 4.2)

https://doi.org/10.1210/en.2006-0027

PubMed

Shrivastava A, Tiwari M, Sinha RA, Kumar A, Balapure AK, Bajpai VK, Sharma R, Mitra K, Tandon A, and Godbole MM. Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving mitochondria-mediated pathway. Journal of Biological Chemistry 2006; 281(28): 19762-19771.

https://doi.org/10.1074/jbc.M600746200

PubMed

Upadhyay G, Singh R, Kumar A, Kumar S, Kapoor A, Godbole MM. Severe hyperthyroidism induces mitochondria-mediated apoptosis in rat liver. Hepatology 2004; 39(4):1120-1130. (Impact Factor 17.4)

https://doi.org/10.1002/hep.20085

PubMed

Singh R, Upadhyay G, Kumar S, Kapoor A, Kumar A, Tiwari M, Godbole MM. Hypothyroidism alters the expression of Bcl-2 family genes to induce enhanced apoptosis in the developing cerebellum. J Endocrinology 2003 176(1):39-46. (Impact Factor 4.2)

10.1677/joe.0.1760039

PubMed

Kumar A, Dharmadheeran JS, Kumar A, Thakral SS. Strain Characterization of vp1/vp2 gene of Canine Parvovirus of Indian origin. Journal of Applied Animal Research, 2004;25: 56-60. (Impact Factor 1.9)

https://doi.org/10.1080/09712119.2004.9706475

Book

o Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against SARS-CoV2 Pandemic. Editors: Raju Khan, Arpana Parihar, Ajeet Kaushik & Ashok Kumar. Elsevier Publication 2022.

ISBN- 9780128244944

Elsevier Publication Book Details

Book

o Computational approaches for novel therapeutic and diagnostic designing to mitigate SARS-CoV2 infection. Editors: Arpana Parihar, Raju Khan, Ashok Kumar, Ajeet Kaushik & Hardik Gohel. Elsevier Publication 2022

ISBN-9780323911726 (Paper Back)

Elsevier Publication Book Details

Book

o Diagnostic, prognostic and therapeutic role of microRNAs in head and neck cancer. Editors: Ashok Kumar, Neha Arya, Shikha Tiwari & Raju Khan. Elsevier Publication. 2024

Paperback ISBN: 9780443159688, eBookISBN: 9780443159695

Elsevier Publication Book Details

Book Chapter

Kulkarni P, Pandey R, Kumar A, Arya N, Das S. miRNAs in the management of nutritional deficiencies and cachexia in head and neck cancer patients. In: Diagnostic, prognostic and therapeutic role of microRNAs in head and neck cancer. Editors: Ashok Kumar, Neha Arya, Shikha Tiwari & Raju Khan. Elsevier Publication. 2024

Book Chapter

Das S, Mohan AJ, Patil D, Kadu N, Kumar V, Brahmachari S, Murali M, Kanwar RK, Joshi D, Kumar A, Arya N. Genome-wide discovery and prediction of microRNA-based biomarkers in head and neck squamous cell carcinoma. In: Diagnostic, prognostic and therapeutic role of microRNAs in head and neck cancer. Editors: Ashok Kumar, Neha Arya, Shikha Tiwari & Raju Khan. Elsevier Publication. 2024

Book Chapter

Tiwari, Kumar A, Kumar V, Sharma P. miRNA expression profiling for Head and Neck cancer (HNC) progression assessment. In: Diagnostic, prognostic and therapeutic role of microRNAs in head and neck cancer. Editors: Ashok Kumar, Neha Arya, Shikha Tiwari & Raju Khan. Elsevier Publication. 2024

Book Chapter

6. Sharma J, Choudhary S, Arya N, Joshi D, Mishra R, Behera G, Kumar A. MicroRNA Regulation of Different Subtypes of Head and Neck malignancies. In: Diagnostic, prognostic and therapeutic role of microRNAs in head and neck cancer. Editors: Ashok Kumar, Neha Arya, Shikha Tiwari & Raju Khan. Elsevier Publication. 2024 (In Press)

Book Chapter

Pandey R, Kanwar JR, Kumar D, Gupta V, Kumar A. Molecular dynamics of autophagy in cancer metabolism. In: Autophagy and Metabolism- Potential Target for Cancer Therapy. Eds: Dhruv Kumar, Shailendra Asthana. Academic Press 2022.

Paperback ISBN: 9780323998796; pp58-88

Book Chapter

Arfin S, Agrawal K, Kumar A, Kumar A, Rathi B and Kumar D. Metabolic dysregulation in cancer progression: Autophagy and Metabolism- Potential Target for Cancer Therapy. Eds: Dhruv Kumar, Shailendra Asthana. Academic Press 2022.

Paperback ISBN: 9780323998796; pp-18-56

Book Chapter

Singh H, Motwani M, Kumar A, Baig MS, Kumar K, Saluja R. Isolation of DNA from blood samples by salting method. In: DNA and RNA Isolation Techniques for Non-Experts. By Springer, Cham. 2022. Eds Akash Gautam.

Hardcover ISBN: 978-3-030-94229-8

Book Chapter

Nema R. Narayan A, Kumar A, Motwani M, Saluja R. Applications of DNA Sequencing Technologies for Current Research. In: DNA and RNA Isolation Techniques for Non-Experts. By Springer, Cham. 2022. Eds Akash Gautam.

Hardcover ISBN: 978-3-030-94229-8

Book Chapter

Prasad S, Srivastava A, Singh N, Singh H, Saluja R, Kumar A, Yadav N, Qidwai T. Present and Future challenges in therapeutic designing using computational approaches. In: Arpana Parihar, Ajeet Kaushik & Ashok Kumar, Raju Khan (Editors). Computational approaches for novel therapeutic and diagnostic designing to mitigate SARS-CoV2 infection. 2022, Academic Press, p489-505. PMCID: PMC9300749,

Full Text

Book Chapter

. Sindhuja T, Kumari R. Kumar A. Epidemiology and pathogenesis of novel coronavirus (SARS-CoV-2). In: Arpana Parihar, Ajeet Kaushik & Ashok Kumar, Raju Khan (Editors). Computational approaches for novel therapeutic and diagnostic designing to mitigate SARS-CoV2 infection. 2022, Academic Press; p23-42; PMCID: PMC9300483

Full Text

Book Chapter

13. Singh H, Nema R, Kumar A. Biomarkers (Genomic and Proteomic) and risk factors associated with SARS-CoV-2 virus. In: Raju Khan, Arpana Parihar, Ajeet Kaushik, Academic Press 2022, ISBN- 978-0-128-24494-4.

Full Text

Book Chapter

Gupta D, Awadhiya O, Saigal S, Kumar A. Structure, genomic analysis, and pathogenesis of SARS-CoV-2 In: Raju Khan, Arpana Parihar, Ajeet Kaushik, Academic Press, 2022. ISBN- 978-0-128-24494-4.

Full Text

Book Chapter

Raj S., Kumar A., Kumar D. (2021) Regulation of Glycolysis in Head and Neck Cancer. In: Hu S. (eds) Cancer Metabolomics. Advances in Experimental Medicine and Biology, vol 1280. Springer, Cham.

Full Text

Book Chapter

Emerging technologies for salivary biomarkers in cancer diagnostics. In: Raju Khan, Arpana Parihar, Sunil Sanghi, editors. Biosensor Based Advanced Cancer Diagnostics. Elsevier Publication (ISBN 978-0-12-823424-2), 2021; pp. 322-339.

Full Text

Book Chapter

Kumar A. Bioavailability and potential uses of micronutrients in food system. In: Singh KK, Tripathi MK, Mangraj S, editors. Bioprocessing of Food and By-products for Nutritional and Industrial Uses. New Delhi: International Books & Periodicals Supply Service (); 2020; pp. 125-137.

ISBN 978-93-88892-09-4

Book Chapter

Kumar A. and Tandon A. Molecular Diagnostics for Lung Cancer. In: Shukla KK, Sharma P, Mishra S, editors. Molecular Diagnostics in Cancer Patients, Springer-Nature Publications. 2019

Book Chapter

Kumar A* and Saba JD. Sphingosine-1-Phosphate. In: Sangdun Choi (Ed). Encyclopedia of Signaling Molecules. Springer Publication, Cham; 2018; 2 Print ISBN 978-3-319-67198-7)

Full Text

Book Chapter

Kumar A* and Saba JD. Sphingosine-1-Phosphate. InSangdun Choi (Ed). Encyclopedia of Signaling Molecules. Springer Publication. 2012, p1771

Salivary transcriptomic biomarkers for the screening of Oral Squamous Cell Carcinoma.

DHR

Extramural

PI

Ongoing

 Screening of CGG repeat in FXTAS, monogenic disorder in Indian patients and its role and mitochondrial dysfunction and mitochondrial mediated inflammation.

ICMR

Extramural

PI

Ongoing

Identification and validation of early predictive biomarkers of acute kidney injury in patients with acute respiratory distress syndrome.

DRDO

Extramural

PI

Ongoing

Understanding the mechanism for aberrant expression of Sphingosine Kinase 1 in oral squamous cell carcinoma.

ICMR

Extramural

PI

Ongoing

Unravelling chemoresistance and S1P signalling in a bioengineered 3-D oral squamous cell carcinoma model: implications in cancer therapy.

ICMR

Extramural

PI

Ongoing

Setting up of registry and targeted exome sequencing in children with renal tubular disorders.

ICMR

Extramural

Co-PI

Ongoing

Development of Rapid Electrochemical based Diagnostics for Detection of SARS-CoV-2 Infection.

SERB

Extramural

Site-PI

Ongoing

Developing CRISPR/Cas9 proximity ligation assay (PLA) for the diagnosis of mitochondrial DNA mutations of complex-I showing and its heteroplasmy in human cell lines types from different origin.

DBT

Extramural

Site-PI

Approved

A) Establishment of DBT NIDAN Kendra at AIIMS Bhopal for Genetic Disorders in Central India And B) Adoption of Aspirational District for Screening of pregnant women and newborns for Genetic Disorders in Vidisha District of Madhya Pradesh. PI &

DBT

Extramural

Co-PI

Approved

Setting up of registry for renal complications in Indian children with Sickle Cell Disease: The Indian Sickle Cell Nephropathy (ISN) Consortium.

ICMR

Extramural

Co-PI

Ongoing

Elucidating cancer-associated adipocytes-mediated metastasis in a 3-D biomimetic co-culture model: applications in breast cancer therapy.

SERB

Extramural

Co-PI

Ongoing

A clinical and molecular study to explore the effect of Homoeopathy in Psoriasis.

CCRH

Extramural

Co-PI

Ongoing

Casein kinase-1ε as a novel therapeutic target against small cell lung cancer.

DoD, USA

Extramural

Co-PI

Approved

Inhibition of RET Proto-Oncogene as novel immune-based Strategy against SCLC.

DoD, USA

Extramural

Co-PI

Approved

Clinicopathological and molecular profiling of adult and paediatric cases of Membranous Nephropathy.

ICMR

Extramural

Co-PI

Ongoing

Prospective, Randomized, Open-Label, Blinded End Point (PROBE), Pilot Clinical Study to Evaluate the Efficacy and Safety of an AYUSH propriety medicine T-AYU-HMTM as an adjunct to Hydroxyurea in the Management of Sickle cell Disease patients.

CCRAS

Extramural

Co-PI

Ongoing/Approved

Flowcytometric analysis of lymphocyte cytokine expression in tubercular effusion samples.

NHM

Extramural

Co-PI

Ongoing

Effect of Music as a medicine on re-entrainment of Circadian Rhythm and stress in Mechanically ventilated patients.

ICMR

Extramural

Co-PI

Ongoing

Prospective evaluation of etiological factors, trajectory of comorbidities and, efficacy and safety of various therapeutic agents among Indian women with Polycystic Ovary Syndrome (PCOS).

ICMR

Extramural

Co-PI

Ongoing

Association and functional characterization of single nucleotide polymorphisms in microRNAs with the susceptibility to oral squamous cell carcinomas.

DHR

Mentored Research Projects

Mentor

Ongoing

Investigating cancer-associated fibroblasts-driven metastasis in a bioengineered 3-D breast cancer co-culture model: towards cancer therapy. 

ICMR

ICMR-SRF to Pallavi Kulkarni

PI

Ongoing

Role of Sphingosine-1-Phosphate signalling pathway in oral carcinogenesis.

SERB

Extramural

PI

Completed

Case Control Study to evaluate the environmental toxins as a cause of Chronic Kidney Disease of Unknown cause (CKD u) in Central India.

Extramural

Co-PI

Completed

Involvement of sphingosine-1-phosphate (S1P) signalling in oral cancer patients.

SERB

Extramural

PI

Completed

Role of Sphingosine-1-Phosphate signaling pathway in lung carcinogenesis.

Madhya Pradesh Council of Science & Technology

Extramural

PI

Completed

MicroTumor Tek: A high throughput screening platform for personalized therapy.

BIRAC

Extramural

Co-PI

Completed

Role of Sphingosine-1-Phosphate and RORs signaling pathway in lung carcinogenesis.

DHR-ICMR

Mentor

Completed

Deciphering the role of Sphingosine-1-Phosphate signaling pathway in tongue squamous cell carcinoma.

ICMR

PI

Completed

co-culture model: Role in breast cancer therapy.

ICMR

ICMR-SRF to Jaya Thilakan

Co-PI

Completed

Kumar A, Singh H, Biswas D, Khan F, Khan R, Sadique MA, Shrivastava AK, Indian Patent application “SARS-COV-2 nucleocapsid antibody detection kit;  

202221046338, dated 20 July 23.

Granted

Arya N, Kulkarni P, Kumar P, Kumar A, Taha M, Hussain M. A high throughput method for preparation of 3-D tumors, Indian Patent, Status: Filed, 2022,

Patent Number: TEMP/E-1/63184/2022-MUM.

Granted

Society Medal by the Society of Life Sciences of India for remarkable contribution to Life Sciences

2023

Fellow of Royal Academy of Biology (FRSB), London

2021

Early Career Research Award (Fast Track Scheme for Young Scientists)

2014

Prof. SS Agarwal award for excellence in research

Jan 2008

American Thyroid Association’s “Travel Grants for Young Investigator” award

Oct 2005

Department of Science & Technology, International travel support to attend conference

2005

CSIR (Young Scientist/Research Scholar) Travel Grant

2005

Sanjay Gandhi Postgraduate Institute of Medical Sciences merit scholarship

Jun 2001-Dec 2001

Department of Biotechnology, Government of India, Merit Scholarship during postgraduate study

Aug 1998- July 2000

GB Pant Univ. Ag. & Technology, Pantnagar ‘s University Graduate Teaching Assistantship award

Jan 1998-June 1998

 Nov 23

 International Conference on Advances and Innovations in Biotechnology for Sustainable Bioresources and Bioeconomy

AKS university, Satna.

Delivered an invited talk on Sphingosine-1-Phosphate signalling Pathway in Cancer Progression and prognosis.

 Sep 2023

National CME on Rare Diseases.

AIIMS Bhopal

Chaired a Session on In Born Errors or Metabolism, organized by the Department of Paediatrics, Anatomy & Pathology & Lab Medicine.

 Sep 2023.

National CME on Rare Diseases

AIIMS Bhopal

Served as a Resource person for Pre-CME Hands-on Workshops on ‘Basics of Flow Cytometry’ and ‘Basics of PCR’ organized by the Department of Paediatrics, Anatomy &Pathology & Lab Medicine.

Aug 25-26, 2023

All India undergraduate Academic in Biotechnology.

Bhagalpur, Bihar

Delivered an Expert Lecture on “Innovative Approaches for Cancer Therapy”.

29th Mar 2023

Workshop on Basics of Flow Cytometry.

AIIMS Bhopal

Served as resource person and delivered a talk in “Workshop on Basics of Flow Cytometry Workshop” organized by Department of Pathology & Lab Medicine.

16-17 Mar 2023

Department of Microbiology

AIIMS Bhopal

Served as resource person and delivered two lectures in “Hands-on basic Flow Cytometry Workshop to advance research in Infectious Diseases” .

22-23 Sep 20222

Inder-disciplinary Research in Cancer Biology.

UPES University, Dehradun.

Delivered an Invited talk on “Therapeutic targeting of Sphingolipid signalling pathway in oral cancer” organized by School of Health & Technology.

March 8, 2022.

National webinar on “Nutraceuticals and Dietary Supplements: Applications in Health Improvement and Disease Management”

(CIAE), Bhopal

Delivered an invited talk on ‘Functional Foods in Wellness and disease prevention’ in organized by ICAR-Central Institute of Agricultural Engineering.

March 15-19, 2021

XLIV Indian Social Science Congress.

Vidisha, M.P

Delivered a Keynote address on “Role of Sphingolipids in Cancer” in the Medical and Health Science Research Committee of the, Samrat Ashok Technological Institute.

24-25 Feb 2021

Workshop on “Innovations in Material Science for Biomedical Applications”

CSIR-AMPRI, Bhopal

 In: SERB supported Organized by on.

Sep 10, 2020

Refresher Course in Life Sciences.

Ranchi University

Delivered a guest lecture (online) Applications of laboratory animals in biomedical research.

Sep 08 2020

Refresher Course In Life Sciences

Ranchi University

Delivered a guest lecture (online) Pathogenesis of SARS-Cov2.

May 23, 2020

Webinar in the series of Advances in Biotechnology for Health, Food and Nutrition to encounter COVID-19

AKS University, Satna

Delivered a webinar Pathogenesis of SARS-Cov2.

Feb 5-7, 2020

39th Annual Convention of Indian Association for Cancer Research

Trivandrum

Delivered an invited talk on Potential role of Lipid Phosphate Phosphatase 3 in Oral Squamous Cell Carcinoma.

5-7 April, 2019

International Conference on Advances and Innovations in Biotechnology for Sustainable Development

AKS University, Satna (MP)

Delivered an invited talk on S1P signaling pathway: A novel therapeutic target for Oral Cancer.

March 1-3, 2019

38th Annual Convention of Indian Association for Cancer Research.

Chandigarh

Sphingosine-1-Phosphate metabolic pathway is altered in Oral Carcinogenesis.

14th-16th Dec 2018

International Symposium on Molecular Medicine

SGPGIMS, Lucknow

Delivered an invited talk on Sphingosine-1-Phosphate Signalling in Colon and Oral Cancer.

 Nov 2018

National Seminar on “Radiopharmaceuticals in Healthcare System: Safety and Regulatory Aspects”.

People’s University, Bhopal (M.P)

Delivered an invited talk on Basics of Radiation Biology and application of
Radiopharmaceuticals in Diagnostics

31 Aug 2018 to 20 Sep 2018

Training programme on “Synergistic approaches for bioprocessing of foods and by-products for nutritional and industrial use”

IACR-CIAE, Bhopal

Delivered an invited talk on Bioavailability and potential uses of micronutrients in food.

May 3-4, 2017

Department of Biotechnology

Bhopal

Signal Transduction: Mechanism of Hormone Actions.

Mar 20-26, 2017

National Workshop on Recent Advances in Genomics and Bioinformatics for Genome Analysis.

AKS University, Satna

Delivered a guest lecture on “Advances in genotyping and mutation detection: Era of personalized Medicine.

 Mar 2017

National Seminar on Contemporary Challenges in the implementation of CPCSEA guidelines’

SN Medical College Agra

Delivered an invited lecture on “Applications of Laboratory Animals in Biomedical research”

 Dec 2016

 National Conference of Association of Clinical Biochemists of India (ACBICON)

Mangalore

Delivered an invited lecture on “Altered expression of Sphingosine-1-Phosphate metabolizing enzymes in oral cancer correlate with clinicopathological attributes.

 Feb 2016

 International Conference on Health Implications of Biotechnology

South Bihar, Patna

Delivered a guest lecture on Sphingosine-1-Phosphate (S1P) lyase in Immunity and Cancer .

 2015

MP Council of Science and Technology, Bhopal

.

9th May, 2015

Hands on workshop on ‘All about PCR’

AIIMS Bhopal

Department of Pathology & Lab Medicine and Department of Biochemistry,.

 2015

DNA Sequencing and Genotyping "

MP Council of Science and Technology, Bhopal

.

6th Nov, 2014

Short course on Research Methods in Medical Sciences.

Bhopal Memorial Hospital and Research Centre, Bhopal

Delivered a guest lecture on ‘Research Design for Experimental Studies’ (Invited as Guest speaker).

5th May, 2015

Department of Biotechnology

Barkatullah University, Bhopal

Delivered a guest lecture on ‘Mass Spectrometry’ during Coursework for PhD students . (Invited as Guest speaker).

27th April, 2015

Department of Biotechnology

Barkatullah University, Bhopal

 Delivered a guest lecture on ‘Comet Assay’ during Coursework for PhD students. (Invited as Guest speaker).

19th Sep, 2014

Hands-on training in Bioinformatics on ‘Bioinformatics and Structural Bioinformatics’

Barkatullah University, Bhopal

Delivered a guest lecture on ‘How do cells communicate?’ during organized by on. (Invited as Guest speaker).

, 2014

All India Seminar on “Recent Advances in Biotechnology and Human Health Care”

MPSC Bhopal

Delivered a talk on ‘Applications of Knockout Mice: S1P lyase as a model’ (Invited as Guest speaker and Chairperson of the Session).

, 2013

winter school

Bhopal (ICAR)

Delivered a talk on ‘Bioactive compounds in Food Systems (Invited as Guest speaker and Resource person).

 Oct, 2013

Bioinformatics and Structural Bioinformatics

Barkatullah University, Bhopal

Delivered a guest lecture on ‘Molecular signaling in cell systems with Bioinformatics relevance’(Invited as Guest speaker).

, 2013

Bhopal

Delivered a talk on ‘Free Radicals in Human Health and Disease’ at CME on Kayachikitsa organized by Pt. Khushilal Sharma Govt. (Invited as Guest speaker and Resource person).

, 2013

Frontiers in Translational OncoImmunology

AIIMS, Bhopal

, S1P Lyase in Lymphocyte trafficking and Colon Cancer.

March 30, 2012

6th Children Hospital Oakland Research Institute Symposium

, Bandhuvula P, Pandurangan AK, Meng Zhang, Henrik Fyrst and Saba JD. Endothelial S1P lyase is required for efficient lymphocyte trafficking.

June 04, 2010

 CHORI/University of California at Berkeley T32 Seminar

Oakland, CA.

, Oskouian B, Saba JD. S1P Lyase promotes mitotic cell death and is a target for radioprotection.

October 12, 2009

UC Berkeley Tumor Biology Seminar Series

Berkeley, CA

, Oskouian B, Saba JD. S1P Lyase promotes mitotic catastrophe and is a target for radioprotection.

 Nov2005.

 International Thyroid Congress held

Buenos Aires, Argentina

, Sinha RA, Tiwari M, Pal L, Shrivastava A, Godbole MM. Hypothyroidism-enhanced apoptosis in developing rat cerebral cortex involves oxidative stress and p75 mediated pathways.

 Nov2005.

International Thyroid Congress

Buenos Aires, Argentina

, Tiwari M, Shrivastava A and Godbole MM. Pro-Nerve Growth Factor provide apoptotic stimuli during rat cerebellar development under hypothyroidism through p75NTR-Sortilin death signalling.

Abstracts Published in Conference Proceedings

2023

 ACBICON

Thiruvalla, Kerala

Model for drug-screening application presented in the Proceedings of Organized by Believers Church Medical College Hospital, (BCMCH).

14-16 Sep 2023.

International Conference of Cancer Biology.

Madras, Chennai

. Sphingosine Kinase 1 is Upregulated in Oral Squamous cell carcinoma via HIF1α .

Aug 25-26, 2023.

All India undergraduate Academic in Biotechnology.

Bhagalpur, Bihar

 Innovative Approaches for Cancer Therapy”

2022

ACBICON

AIIMS Bhopal

Thilakan J, Kumar A, Khadia R and Arya N. In-situ Biomineralized 3D Silk Fibroin Based Co-culture Model to Study BCA Metastasis.

 Aug, 2022.

 International School of Oncology.

AIIMS Bhopal

. In silico identification of long non-coding RNAs as prognostic biomarkers for invasive breast cancer. (Ms Pooja Received 1  Prize for the Best Podium Presentation).

9th-11th Dec 2021.

47th National Conference of Association of Clinical Biochemists of India (ACBICON).

Kolkata

, Kanwar J, Chowdhary R. Comparative analysis of chemotherapeutic drugs using Temozolomide, Cisplatin and BITC for reverse regulation of oncogenic miRNA in glioblastoma treatment.

9th-11th Dec 2021.

47th National Conference of Association of Clinical Biochemists of India (ACBICON).

Kolkata

, Biswas D, Kanwar J, Chowdhary R. Molecular characterization and identification of dengue virus in febrile patients referring at AIIMS Bhopal hospital in central India.

9th-11th Dec 2022.

47th National Conference of Association of Clinical Biochemists of India (ACBICON).

Kolkata

.  Development of tongue squamous cell carcinoma involves downregulation of Lipid phosphate phosphatase 3.

9th-11th Dec 2021.

47th National Conference of Association of Clinical Biochemists of India (ACBICON).

Kolkata

, Saluja R. Elucidating the potential role of Interleukin-33, sST2, and IgE in asthmatic patients.

Feb 2-5, 2022

41st Annual Conference of Indian Association for Cancer Research.

NOIDA

 and Arya N. Development of 3-D spheroid model-based on breast and cervical cancer for drug screening application.

March 15-19, 2021.

XLIV Indian Social Science Congress.

Vidisha, MP

. Prognostic role of Receptor tyrosine kinase like orphan receptors in Gastric Cancer.

March 15-19, 2021

XLIV Indian Social Science Congress.

Vidisha, MP.

. Expression of Sphingosine-1-Phosphate Phosphatase 1 correlates with better prognosis and tumor-infiltrating immune cells in triple-negative breast cancer patients.

March 15-19, 2021.

XLIV Indian Social Science Congress.

Vidisha, MP.

. Ceramide metabolizing enzymes associate with the prognosis of non-small cell lung cancer: an in-silico analysis.

March 15-19, 2021.

XLIV Indian Social Science Congress held at Samrat Ashok Technological Institute.

Vidisha, MP.

, Nema R and Shrivastava A. Prognostic role of Sphingosine-1-Phosphate Signaling Genes in Lung Cancer: TCGA analysis.

March 15-19, 2021.

XLIV Indian Social Science Congress held at Samrat Ashok Technological Institute.

Vidisha, MP

., Saluja R., Deciphering the potential role of Interleukin-33 in asthmatic patients.

15-17th March 2021

44th Indian Social Science Congress.

Vidisha, India

, Association of Single Nucleotide Polymorphisms (SNPs) with the susceptibility to Oral Cancer.

5-7 April, 2019

International Conference on Advances and Innovations in Biotechnology for Sustainable Development.

AKS University, Satna (MP)

Pandey R, Vishwakarma S, Nema R, Singh R, Singh AP, Kumar A. Single Nucleotide Polymorphisms (SNPs) in cytokine genes associated with the risk for Oral Cancer.

24-27 Oct 2018.

ACBICON 2018

Goa, India

 (-308), IL-12A (3’UTR) and IL-6 (-572) Single Nucleotide  Polymorphisms (SNPs) decrease the risk for Oral Cancer.

2018

ESMO

Differential expression of Sphingosine-1-Phosphate metabolizing enzymes in oral squamous cell carcinoma  Open :;3 (Suppl 2), A123

Feb 9-11, 2017

36th Annual Conference of Indian Association for Cancer Research.

Trichur, KA.

, Agarwal R. Gene expression of Sphingosine-1- Phosphate metabolizing enzymes in oral cancer patients and their correlation with clinicopathological features.

15-17th Sept.2017

37th ICON.

New Delhi, India.

, Agarwal R, Singh R, Expression of Sphingosine-1 Phosphate metabolizing enzymes and long non-coding RNAs in oral squamous cell carcinoma.

 Dec 2016.

 National Conference of Association of Clinical Biochemists of India (ACBICON).

Mangalore

Kumar A, Vishwakarma S, Agarwal R. Altered expression of Sphingosine-1-Phosphate metabolizing enzymes in oral cancer correlate with clinicopathological attributes.

 April 2015

 Centuary.

Barkatullah University, Bhopal

. Sphingosine kinase 2 is down-regulated in tumor tissue of head and neck cancer patients.

June 1-6, 2014.

FASEB Conference on ‘Phospholipid Cell signalling and Metabolism in Inflammation and Cancer’.

Niagara Falls, NY USA,

, Bandhuvula P, Eltanawy A, Zhang M, and Saba JD. SPL in dendritic cells promotes T lymphocyte egress from thymus*. *Won best poster award

April 22 - April 27, 2009.

Keystone symposium, Complex Lipids in Biology: Signalling, Compartmentalization and Disease.

Olympic Valley, CA

, Oskouian B, Saba JD. S1P lyase enhances apoptosis in response to genotoxic drug and radiation by releasing the cells from G2/M arrest.

Dec 13-17, 2008.

 Annual Meeting of American Society for Cell Biology Annual.

San Francisco

, Oskouian B, Saba JD. Sphingosine-1-Phosphate lyase enhances radiation-induced apoptosis by releasing the cells from G2/M arrest.

May 5-May 6 2008

Partial-Body Radiation Diagnostic Biomarkers and Medical Management of Radiation Injury Workshop.

Bethesda, MD

Novel Sphingolipid Biomarkers of Gut Injury Induced by Radiation.  

Dec 13-15 2006

International Conference held on at National Brain research Centre.

Gurgaon, India.

, Pathak A, Tiwari M, Shrivastava A, Godbole MM. Involvement of p75NTR during increased neonatal neuronal cell death under thyroid hormone deficiency in rats.

Dec 13-15 2006

 International Conference: held on at National Brain research Centre.

Gurgaon, India

, Pal L, Godbole MM. Expression of nitric oxide synthase and vascular endothelial growth factor in ischemia-reperfusion: relationship to euthyroid and hypothyroid rats.

Jan 18-20, 2006

XIX All India Cell Biology Conference & Symposium on Gene to Genome: Environment and Chemical Interaction.

Industrial Toxicology Research Centre, Lucknow , India

, Sinha RA, Tiwari M, Pal L, Shrivastava A, Godbole MM Hypothyroidism-enhanced apoptosis in developing rat cerebral cortex involves oxidative stress and p75 mediated pathways.

October 30-November 4, 2005

13th International Thyroid Congress

Buenos Aires, Argentina

, Sinha RA, Tiwari M, Pal L, Shrivastava A, Godbole MM. Hypothyroidism-enhanced apoptosis in developing rat cerebral cortex involves oxidative stress and p75 mediated pathways.

Oct 30-Nov 4, 2005.

13th International Thyroid Congress.

Buenos Aires, Argentina

, Tiwari M, Shrivastava A and Godbole MM. Pro-Nerve Growth Factor provide apoptotic stimuli during rat cerebellar development under hypothyroidism through p75NTR-Sortilin death signaling.

 June 2005

 Annual Meeting of Cold Spring Harbor Laboratory.

New York

 Sinha RA, Balapure AK, Sharma R, Shahashrabudhhe AK, Shrivastava A, Babu S. Bajpai VK. Mechanism of 4-Hydroxy Phenyl Retinamide Induced Apoptosis in Glioblastoma cell lines.

26-28 November 2004

 National conference of Endocrine Society of India

Guwahati, India

 Sinha AK, Shrivastava A, Tiwari M, Pal L  & Godbole MM. Hypothyroidism augments apoptosis in developing rat cerebral cortex.

26-28 November 2004

 National conference of Endocrine Society of India.

Guwahati, India.

 Pal L, Trivedi P, Tiwari M, Sinha RA, & Godbole MM. Recombinant human sodium/iodide symporter (hNIS) synthesis, development of specific antibody and evidence of hNIS alternate spliced variant in thyroid and breast tumors.

15-17 December 2003

International Symposium: Building the brain.

Gurgaon, India

 Tiwari M, Pal L, Shrivastava A and Godbole MM. Hypothyroidism augments apoptosis in developing rat cerebral cortex independent of mitochondrial-mediated pathway.

15-17 December 2003

International Symposium: Building the brain.

Gurgaon, India

 Balapure AK, Sharma R, Shrivastava A and Godbole MM. 4-hydroxy phenyl retinamide induces apoptosis in highly malignant glioma cell lines as compared with natural retinoids.

22-25 December 2003

Conference on Thyroid Hormone and Brain Development

NIEHS, Research Triangle Park, NC.

 and Tiwari M. Hypothyroidism alters mitochondrial morphology and induces release of apoptogenic proteins during developing rat cerebellum.

2004

Reactive oxygen species and membrane permeability transition are involved in 4-HPR induced apoptosis in glioblastoma multiforme derived cell lines . Proceedings of the American Association for Cancer Research (1), 1194

October 9-13, 2002

74th Annual Meeting of the American Thyroid Association

Los Angeles, CA

 Tiwari M and Godbole MM. Hyperthyroidism induces apoptosis in the adult cerebral cortex: Direct action of T3 on mitochondria.

Poster Presentations at Conferences/Symposium

 July 2018

 Biennial Congress of the European Association for Cancer Research.

Amsterdam, Netherlands.

1. Differential expression of Sphingosine-1-Phosphate metabolizing enzymes in oral squamous cell carcinoma.

 Dec 2022.

Conference of Association of Physiologists and Pharmacologists of India (APPICON)

Chandigarh.

, Pakhare A. Impact of fibromyalgia severity on mood, sleep quality and quality of life of patients with fibromyalgia.

Feb 3-5, 2018.

 World Cancer Congress (WCC).

Jaipur

 Joshi D, Singh R, Kapoor N, Singhal R. Expression of Sphingosine-1-Phosphate metabolizing enzymes and long-non-coding RNAs is altered in oral squamous cell carcinoma patients.

 Nov 2017

 Indian Cancer Congress  .

Bengaluru

 Joshi D, Singh R, Kapoor N, Singhal R. Aberrant expression of Sphingosine-1-Phosphate metabolizing enzymes and long non-coding RNAs in oral squamous cell carcinoma patients.

March 10-11, 2017.

32nd MP Young Scientist Congress.

Vigyan Bhawan, Bhopal.

, Gene expression of Sphingosine-1-Phosphate metabolizing enzymes in oral cancer patients and their correlation with clinicopathological features.

Feb 9-11, 2017.

36th Annual Conference of Indian Association for Cancer Research.

Trichur, KA

, Agarwal R. Gene expression of Sphingosine-1- Phosphate metabolizing enzymes in oral cancer patients and their correlation with clinicopathological features.

March 30, 2012.

 Children Hospital Oakland Research Institute Symposium.

Oakland, USA  

, Bandhuvula P, Zhang M, Fyrst H and Saba JD. S1P lyase deficiency augments colitis-associated colon cancer through STAT3 pathway.

March 30, 2012.

 Children Hospital Oakland Research Institute Symposium.

Oakland,  USA

 and Saba JD. The effect of sphingadiene treatment on neuroblastoma cells.

March 30, 2012.

 Children Hospital Oakland Research Institute Symposium.

Oakland, USA

, Fyrst H, Zhang M, Proia R, Hoffman EP and Saba JD. Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscle through an S1PR2/STAT3 signaling pathway.

May 31, 2010

 Children Hospital Oakland Research Institute Symposium.

Oakland, USA

, Oskouian B, Henrik Fyrst, Francios Paris, Saba JD. S1P Lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism.

May 23, 2008.

 Children Hospital Oakland Research Institute Symposium.

Oakland, USA

, Oskouian B, Saba JD. Sphingosine-1-phosphate lyase enhances apoptosis through activation of MAP kinase pathways.

Guide

Ms Ritu Pandey

PhD

-

Guide

Ms Pallavi Kulkarni

PhD

-

Co-guide

Mr. Ashish Yadav

PhD

-

Guide

Jahnavi Sharma

PhD

-

Guide

Akanksha Bhattacharya

PhD

-

Co-guide

Anzar Bashir Alvi

PhD

Co-guide

Dr. Riya Rose

MS

Co-guide

Dr. Vandana C Kattimani

MS

-

Co-guide

Dr. Amrita

MD

Doctoral Committee Member

Mr Santen San C

PhD

Co-guide

Ms Arya Mohan

PhD

Doctoral Committee Member

Ms Sayantika Das

PhD

Guide

Ms Himadri Singh

PhD

Dec 2023

Guide

Dr. T. Sindhuja

MD

Jan 2024

Guide

Dr. Ravita Kumari

MD

Dec 2022

Co-guide (BU)

Ms Supriya Vishwakarma

PhD

June 2022

Co-guide

Dr. Poonam Chaudhary

MD

June 2020

Co-guide

Dr. Swati Nema

MDS

Co-guide

Dr. Daideepya Bhargava

MD

Dec 2021

Co-guide

Dr. Aishwarya Shivhare

MD

June 2022

Co-guide

Dr Kailash Mahalda

MD

Dec 2022

Co-guide

Dr. Poorva Ragavan

MD

June 2022

Guide

Ms Ritu Pandey

M.Sc

June 2017

Guide

Mr Shivanshu Shukla

M.Sc

June 2018

Guide

Ms Megha Gawande

M.Sc

June 2018

Guide

Ms Shivani Malviya

M.Sc

June 2022

Guide

Ms Sana Hashmi

M.Sc

June 2022

Mentor

Ms Payal Sharma

M.Sc

June 2023

Mentor

Ms Surya Prajapati

M.Sc

June 2023

Mentor

Mr. Subhojit AjitKumar Halder

MBBS (ICMR-STS)

2018

Mentor

Mr. Siddharth Raina

MBBS (ICMR-STS)

2018

Co-Mentor

Mr Himanshu Mishra

MBBS (ICMR-STS)

2017

Mentor

Mr Ajay Pal Singh

MBBS (Intra-mural)

2017

Mentor

Mr Anupam Halder

MBBS (ICMR-STS)

2015

Co-Mentor

Mr. Dilan Davis

MBBS (ICMR-STS)

2015

Mentor

Ms. Sruthy Mohan

MBBS (ICMR-STS)

2014