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Dr. Neha Arya
neha.tmc@aiimsbhopal.edu.in

Associate Professor
Translational Medicine


Education

  • Ph.D., Biological Sciences and Bioengineering (BSBE), Indian Institute of Technology Kanpur, India, 2013
  • Master of Science in Microbiology, University of Delhi, India, 2005
  • Bachelor of Science in Microbiology, University of Delhi, India , 2003


Other Administrative Position/In Charge

Managing Editor, Future Health (Official Journal of AIIMS Bhopal)

Nodal Officer, MoU between AIIMS Bhopal and MANIT Bhopal

Member Secretary, Technical Specification Committee


Area of Interest (Specialty)
Tissue Engineering


Area of Interest (Other)

in vitro tumor models

point-of-care diagnostics


Research Interest
Tissue engineering


Google Scholar


ResearchGate


Telephone

   About

Experienced Biomedical Researcher with a demonstrated history of working in the academia. Strong education professional with expertise in biomaterials-based device development for application in nanotechnology, drug delivery, in vitro disease models as well as regenerative medicine.

   Fellowships/specialization

S.No. Fellowships/specialization Awarded year
1 DST Inspire Faculty Fellowship, Department of Science and Technology, India 2015
2 Post-Doctoral Fellowship, University of Freiburg, Germany 2013
3 Junior Research Fellowship (Life Sciences Stream), Council of Scientific and Industrial Research, India 2005
4 Graduate Aptitude Test in Engineering (Life Sciences Stream), 97.78 percentile, India 2005
5 Monsanto Scholarship, Department of Microbiology, University of Delhi, India (2004-05)
6 National Scholarship, Department of Microbiology, University of Delhi, India (2003-04)

   Publications

S.No. Publications DOI-URL

Sarkar P, Chowdhary R, Ashish Kumar Yadav, Arya N, Pandya B, Kumar V, et al. Unrevealing the Role of miRNA in Successful TNBC Treatment: A Pilot Study to Explore the Chemotherapy Drugs for Timely Treatment of TNBC. Journal of Laboratory Physicians. 2023 Sep 5;

10.1055/s-0043-1774405

Joshi S, Pandey R, Kumar A, Gupta V, Arya N. Targeted blockade of interleukin-8 negates metastasis and chemoresistance via Akt/Erk-NFκB axis in oral cancer. Cytokine. 2023 Jun 1;166:156155–5.

https://doi.org/10.1016/j.cyto.2023.156155

Chatterjee S, Lakshmi Vineela Nalla, Sharma M, Sharma N, Singh AA, Fehmina Mushtaque Malim, et al. Association of COVID-19 with Comorbidities: An Update. 2023 Feb 27;6(3):334–54.

https://doi.org/10.1021/acsptsci.2c00181

Priyanka Pulugu, Arya N, Kumar P, Srivastava A. Polystyrene-Based Slippery Surfaces Enable the Generation and Easy Retrieval of Tumor Spheroids. ACS applied bio materials. 2022 Nov 29;5(12):5582–94.

https://doi.org/10.1021/acsabm.2c00620

Suchita Dattatray Shinde, Rao KB, Santosh Kumar Behera, Arya N, Sahu B. Epithelial cell adhesion molecule (EpCAM) binding short peptides derived from antibody MOC-31; De-novo design, synthesis and their in-vitro evaluation. Biochemical and Biophysical Research Communications. 2022 Apr 1;600:1–5.

https://doi.org/10.1016/j.bbrc.2022.01.120

Piyush Gondaliya, Adil Ali Sayyed, Bhat P, Mali M, Arya N, Amit Khairnar, et al. Mesenchymal Stem Cell-Derived Exosomes Loaded with miR-155 Inhibitor Ameliorate Diabetic Wound Healing. Molecular Pharmaceutics. 2022 May 2;19(5):1294–308.

https://doi.org/10.1021/acs.molpharmaceut.1c00669

Adil Ali Sayyed, Piyush Gondaliya, Bhat P, Mali M, Arya N, Amit Khairnar, et al. Role of miRNAs In Cancer Diagnostics And Therapy: A Recent Update. Current Pharmaceutical Design. 2022 Feb 1;28(6):471–87.

https://doi.org/10.2174/1381612827666211109113305

Vishwakarma S, Arya N, Kumar A. Regulation of tumor immune microenvironment by sphingolipids and lysophosphatidic acid. Current Drug Targets. 2021 Dec 8;22.

https://doi.org/10.2174/1389450122666211208111833

Choppadandi M, Guduru AT, Gondaliya P, Arya N, Kalia K, Kumar H, et al. Structural features regulated photoluminescence intensity and cell internalization of carbon and graphene quantum dots for bioimaging. Materials Science and Engineering: C. 2021 Oct;129:112366.

https://doi.org/10.1016/j.msec.2021.112366

Adil Ali Sayyed, Piyush Gondaliya, Mali M, Pawar A, Bhat P, Amit Khairnar, et al. MiR-155 Inhibitor-Laden Exosomes Reverse Resistance to Cisplatin in a 3D Tumor Spheroid and Xenograft Model of Oral Cancer. Molecular Pharmaceutics. 2021 Jun 28;18(8):3010–25.

https://doi.org/10.1021/acs.molpharmaceut.1c00213

Singh MP, Brahmachari S, Arya N. An elderly woman with multilobulated breast mass presenting as a diagnostic dilemma: A rare case report. Journal of Family Medicine and Primary Care [Internet]. 2021 Oct 1

https://doi.org/10.4103%2Fjfmpc.jfmpc_176_21

Pulugu P, Ghosh S, Rokade S, Choudhury K, Arya N, Kumar P. A perspective on implantable biomedical materials and devices for diagnostic applications. Current Opinion in Biomedical Engineering. 2021 Jun;18:100287.

https://doi.org/10.1016/j.cobme.2021.100287

  1.  

Kulkarni N, Shinde SD, Jadhav GS, Adsare DR, Rao K, Kachhia M, et al. Peptide-Chitosan Engineered Scaffolds for Biomedical Applications. Bioconjugate Chemistry. 2021 Mar 3;32(3):448–65.

https://doi.org/10.1021/acs.bioconjchem.1c00014

Arya N, Forget A, Melika Sarem, V. Prasad Shastri. RGDSP functionalized carboxylated agarose as extrudable carriers for chondrocyte delivery. Materials Science and Engineering: C. 2019 Jun 1;99:103–11.

https://doi.org/10.1016/j.msec.2019.01.080

Ahrens L, Vonwil D, Arya N, Forget A, Shastri VP. Biotin-Avidin-Mediated Capture of Microspheres on Polymer Fibers. Molecules. 2019 May 28;24(11):2036.

https://doi.org/10.3390/molecules24112036

Biomaterials for recapitulating tumor’s extracellular matrix: towards personalized therapy‬ [Internet]. scholar.google.de. [cited 2024 Feb 15].

http://dx.doi.org/10.1007/978-981-10-3328-5_8

Kumar A, Arya N. Mfsd2b, a Novel Sphingosine-1-Phosphate Transporter: Implication in Cancer Therapeutics. 2018 Jan 1;07(02).

10.4172/2324-9110.1000e113

Melika Sarem, Arya N, Heizmann M, Neffe AT, Barbero A, Gebauer T, et al. Interplay between stiffness and degradation of architectured gelatin hydrogels leads to differential modulation of chondrogenesis in vitro and in vivo. 2018 Mar 15;69:83–94.

https://doi.org/10.1016/j.actbio.2018.01.025

Forget A, Arya N, Rotsiniaina Randriantsilefisoa, Florian Miessmer, Buck M, Ahmadi V, et al. Nonwoven Carboxylated Agarose-Based Fiber Meshes with Antimicrobial Properties. Biomacromolecules. 2016 Nov 22;17(12):4021–6.

https://doi.org/10.1021/acs.biomac.6b01401

Lamichhane SP, Arya N, Kohler E, Xiang S, Christensen J, Shastri VP. Recapitulating epithelial tumor microenvironment in vitro using three dimensional tri-culture of human epithelial, endothelial, and mesenchymal cells. BMC Cancer. 2016 Aug 2;16(1).

10.1186/s12885-016-2634-1

Katti D, Arya N. Poly(d,l-lactide-co-glycolide)–chitosan composite particles for the treatment of lung cancer. International Journal of Nanomedicine. 2015 Apr;2997.

  • 10.2147/IJN.S78120

22.

Shastri P, Lamichhane S, Arya N, Ojha N, Kohler E. Glycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake. International Journal of Nanomedicine. 2015 Jan;775.

  • 10.2147/IJN.S73508

23.

Arya N, Arora A, Vasu KS, Sood AK, Katti DS. Combination of single walled carbon nanotubes/graphene oxide with paclitaxel: a reactive oxygen species mediated synergism for treatment of lung cancer. Nanoscale. 2013;5(7):2818.

https://doi.org/10.1039/C3NR33190C

24.

tumour model. Journal of the Royal Society Interface. 2012 Sep 12;9(77):3288–302.

https://doi.org/10.1098/rsif.2012.0564

25.

Arya N, Chakraborty S, Dube N, Katti DS. Electrospraying: A facile technique for synthesis of chitosan-based micro/nanospheres for drug delivery applications. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2009 Jan;88B(1):17–31.

https://doi.org/10.1002/jbm.b.31085

26.

In situ collagen mineralization modulates metastatic properties of breast cancer cells

   Book/ Book Chapter

S.No. Book / Book Chapter Title DOI-URL

Advanced Biosensors for Virus Detection Smart Diagnostics to Combat SARS-CoV-2

Optical biosensors for SARS-CoV-2 detection

https://doi.org/10.1016/B978-0-12-824494-4.00005-9

In Nano bioanalytical Approaches to Medical Diagnostics

Point-of-care diagnostics for cancer: recent trends and challenges

https://doi.org/10.1016/B978-0-323-85147-3.00006-2

Biosensor Based Advanced Cancer Diagnostics

Emerging technologies for salivary biomarkers in cancer diagnostics

https://doi.org/10.1016/B978-0-12-823424-2.00021-1

Immobilization Strategies

Cell Immobilization Strategies for Tissue Engineering: Recent Trends and Future Perspectives

https://doi.org/10.1007/978-981-15-7998-1_2

Biomaterials in orthopaedics and bone regeneration, Materials Horizons: From Nature to Nanomaterials

Engineering of bone: uncovering strategies of static and dynamic environments

https://doi.org/10.1007/978-981-13-9977-0_12

Advances in Biomaterials for Biomedical Applications

Biomaterials Based Strategies for Engineering Tumor Microenvironment

https://doi.org/10.1007/978-981-10-3328-5_8

Advanced Biomaterials: Fundamentals, Processing and Applications

Designing nano fibrous scaffolds for tissue engineering

https://doi.org/10.1002/9780470891315.ch13

   Projects

S.No. Title of Project Funding Agency PI/Co-PI Extramural/  Intramural Completed/Running

“Effect of mechanically graded nano-fibrous scaffolds on cancer cell migration: Applications in anti-metastatic agent screening/testing”

Department of Science and Technology, Government of India

Extramural

Completed

Implications in breast cancer therapy”

Science and Engineering Research Board (SERB) under Early Career Research Award Category

Extramural

Completed

MicroTumor Tek: A high throughput-screening platform for personalized therapy”

Biotechnology Industry Research Assistance Council under BIG Scheme, India

Extramural

Completed

“Deciphering CXCR4/CXCL12 signaling on a tissue engineered bone-mimetic 3-D in vitro co-culture model: Role in breast cancer therapy”

Indian Council of Medical Research-Senior Research Fellowship Category

PI

Ongoing

  1.  

“Investigating cancer-associated fibroblasts-driven metastasis in a bioengineered 3-D breast cancer co-culture model: towards cancer therapy”

Indian Council of Medical Research-Senior Research Fellowship Category

Co-PI

Ongoing

  1.  

“Elucidating cancer-associated adipocytes-mediated metastasis in a 3-D biomimetic co-culture model: applications in breast cancer therapy”

SERB Government of India

PI

Ongoing

“Establishment of “Tissue Engineering Facility” at the Department of Translational Medicine Centre”

Vardhman Group under their CSR initiative

PI

Ongoing

“Identification of urinary exosomal miRNA for early detection of breast cancer: toward non-invasive diagnostics”

M.P. Council of Science & Technology

PI

Ongoing

“Investigating the role of environmental pollutants in population of Singrauli district, Madhya Pradesh and human lung organoids”

M.P. Pollution Control Board

PI

Ongoing

10.

“Evaluating the health impact of environmental pollutants in population of Sonebhadra district, Uttar Pradesh and laboratory-based three dimensional human lung organoid platform”

U.P. Pollution Control Board

PI

Ongoing

11.

“Understanding the mechanism for aberrant expression of Sphingosine Kinase 1 in oral squamous cell carcinoma"

ICMR, Government of India

Co-I

Ongoing

12.

Development of a home-based sleep monitoring device for screening of obstructive sleep apnea using wearable sensors and mobile technology

ICMR, Government of India

Co-I

Ongoing

13.

Unravelling chemoresistance and S1P signalling in a bioengineered 3-D oral squamous cell carcinoma model: implications in cancer therapy”

ICMR

Co-PI

Ongoing

14.

Screening synthetic extracellular matrix for culturing patient derived breast cancer cells: towards personalized therapy”

Department of Science and Technology under DST-DAAD under Project- based Personnel Exchange Programme with India

Co-PI

Ongoing

   Patent

S.No. Patent Status

A high throughput method for preparation of 3-D tumors, Patent Application Number E-2/1899/2023/MUM, Indian Patent

Filed

A method for tumoroid generation using 3-D chitosan-gelatin scaffolds for anti-cancer drug screening, Patent Application Number 2841/Del/2012, Indian Patent, Patent Number: 443023

Granted, 2023,

A process for synthesis of polymeric micro/nano-particles for drug (bioactive agent) delivery applications, Patent Application Number 645/Del/2008, Indian Patent, Patent Number: 285405

Granted, 2017

   Award

S.No. Award Awarded year
1 Second Prize (Poster Presentation), 2nd International Global Cancer Consortium Conference, Manipal. (As Co-author in the abstract) 2023
2 Second Prize (Oral Presentation), International virtual meet on "Non-Coding RNAs in Health and Disease", All India Institute of Medical Sciences, Bhopal, (as Co-corresponding author in the abstract) 2022
3 Power Grant, Science and Engineering Research Board, Government of India 2022
4 Biotechnology Ignition Grant Awardee, BIRAC 2019
5 Early Career Research Award, Science and Engineering Research Board 2019
6 First Position, SMC Select, Startup Master Class, Indian Institute of Technology-Kanpur, India 2019
7 Best Poster Award, World Congress on Cancer, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, India 2018
8 Bajpai-Saha Award, Third Position (Oral Presentation) and Second Position (Micrography Contest), International Conference on Design of Biomaterials & XXIII Annual Meeting of Society of Biomaterials and Artificial Organs (SBAOI) & VI Annual general Meeting of Society of Tissue Engineering and Regenerative Medicine (STERMI), Indian Institute of Science, Bangalore, India 2012
9 Travel award, Indian Council of Medical Research, India to present research work at 38th Annual Meeting and Exposition of the Controlled Release Society, National Harbor, Maryland, USA 2011
10 Travel award, Department of Science & Technology, India to present research work at Society for Biomaterials, Annual Meeting and Exposition, Orlando, Florida, USA 2011
11 Travel award, Council of Scientific & Industrial Research, India to present research work at Society for Biomaterials, Annual Meeting and Exposition, Orlando, Florida, USA (not availed) 2011
12 Travel award, Department of Biotechnology, India to present research work at 38th Annual Meeting and Exposition of the Controlled Release Society, National Harbor, Maryland, USA and Society for Biomaterials, Annual Meeting and Exposition, Orlando, Florida, USA (not availed) 2011
13 Third Position (Oral Presentation), International conference on Design of Biomaterials and XVII Annual Meeting of Society of Biomaterials and Artificial Organs, IIT Kanpur, India 2006
14 Second Position, Bachelors of Science, Department of Microbiology, University of Delhi 2001
15 First Position, Class X, New Delhi, India 1998
16 Certificate of Merit, among the top 0.1% of successful candidates of All India Senior Secondary Examination in Mathematics. 1998
17 Certificate of Merit, National Scholarship Schemes and listed among the meritorious students for CBSE Senior Secondary Examination 1998
18 Certificate of Merit, Delhi Association of Mathematics Teachers, 94% in National Mathematics Olympiad Contest 1997

   Outreach activities

S.No. Date Detail of outreach Your contribution

   Conference/ Workshops

S.No. Date Workshop name Venue place Your contribution

2024

Central Zone Conference of Association of Clinical Biochemists of India

AIIMS Bhopal, Madhya Pradesh

Oral Presentation/ Corresponding author

2024

Central Zone Conference of Association of Clinical Biochemists of India

AIIMS Bhopal, Madhya Pradesh

Poster Presentation/ Corresponding author

2023

 International Global Cancer Consortium Conference

Manipal

e-Poster Presentation/ Corresponding author

2023

 

Manipal

e-Poster Presentation

2022

48th Annual Conference of Clinical Biochemistry of India, (*)

ICAR Convention Centre, New Delhi

Oral Presentation/ Corresponding author

2022

International virtual meet on "Non-Coding RNAs in Health and Disease"

All India Institute of Medical Sciences, Bhopal

Co-Corresponding author

2022

 International Conference of Indian Association for Cancer Research

Amity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR), Amity University Uttar Pradesh, NOIDA, India

Oral Presentation/ Corresponding author

2022

 International Conference of Indian Association for Cancer Research

Amity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR), Amity University Uttar Pradesh, NOIDA, India

Poster Presentation/ Corresponding author

 July 2022

MEDSER conference cum workshop

IISER Bhopal

Invited Talk

2019

International Conference on Biomaterial-based therapeutic engineering and regenerative medicine

Indian Institute of Technology Kanpur, India

Podium Presentation/ corresponding author

2019

Startup Master Class

Indian Institute of Technology Kanpur, India

Podium Presentation

2018

International Conference on Biomaterials, BioEngineering & BioTheranostics (BioMET 2018)

Vellore Institute of Technology, Vellore, India

 Corresponding Author

2018

World Congress on Cancer

Mahatma Gandhi Medical College and Hospital, Jaipur, India

 Corresponding Author

2015

Orthopaedic Research Society 2015 Annual Meeting

, Las Vegas, USA

Poster Presentation

2014

Tissue Engineering and Regenerative Medicine International Society EU Chapter

Genova, Italy

Poster Presentation

2014

Europeans Material Research Society

Lille, France

Podium Presentation

2014

Makromolekulares Kolloquium Freiburg

Freiburg, Germany

Poster Presentation

2012

International Conference on Design of Biomaterials & XXIII Annual Meeting of Society of Biomaterials and Artificial Organs (SBAOI)& VI Annual general Meeting of Society of Tissue Engineering and Regenerative Medicine (STERMI)

IISc Bangalore, India

Podium Presentation

2012

Science and Communication Workshop

Wellcome Trust- DBT India Alliance, Hyderabad, India

2011

th Annual Meeting and Exposition of the Controlled Release Society

National Harbor, Maryland, USA

Podium Presentation

2011

th Annual Meeting and Exposition of the Controlled Release Society

National Harbor, Maryland, USA

Poster Presentation

2011

Society for Biomaterials, Annual Meeting and Exposition

Orlando, Florida, USA

Podium Presentation

2010

Society for Biomaterials, Annual Meeting and Exposition

Seattle, Washington, USA

Poster Presentation

2009

Intellectual property rights sensitization

Federation of Indian Chambers of commerce and Industry and Intellectual Property Office, Kanpur, India

2007

Developmental Biology and Biomedical Research

Agra, India

Poster Presentation

2007

Summer School, Nanotechnology in Advanced Drug Delivery

National Institute of Pharmaceutical Education and Research (NIPER), Chandigarh, India

Podium Presentation

2006

International conference on Design of Biomaterials and XVII Annual Meeting of Society of Biomaterials and Artificial Organs

IIT Kanpur, India

Podium Presentation

   Guide/Co-Guide/Mentor

S.No. Guide/co-guide/mentor Name of students, Department PG/SR/PhD/MBBS Student Year
1 Co-Guide Dr. Poulami Sarkar PG Student 2019
2 Co-Guide Pallavi Kulkarni, Biochemistry PhD 2019
3 Guide Jaya Thilakan, Biochemistry (Registered in Barkatullah University) PhD 2022
4 Co-Guide Jahnavi Sharma, Biochemistry PhD 2022
5 Guide Sayantika Das, Translational Medicine PhD 2023
6 Guide Arya J Mohan, Translational Medicine PhD 2023
7 Guide Muskan Talreja, Translational Medicine PhD 2024